[Pronostic value of the immunohistochemical expression of cyclin D1 (DCS6) in epidermoid larynx carcinoma]. / Valor pronóstico de la expresión inmunohistoquímica de ciclina D1 en carcinoma epidermoide de laringe.

In this paper we carried out an immunohistochemical study of cyclin D1 (DCS6 ) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain) for a time of 5 years. In the cases with lymph node metastasis we also studied cyclin D1 expression at this level. Furthermore we have analysed the value of cyclin D1 expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between cyclin D1 expression and other clinic and pathologic parameters.

[Prognostic value of the inmunohïstochemical expression of protein p27KIP1 in laryngeal cancer]. / Valor pronóstico de la expresión inmunohistoquímica de la proteína p27KIP1 en cáncer de laringe.

In this paper we carried out an immunohistochemical study of protein p27KIP1 expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain). In the cases with lymph node metastasis we also studied p27KIP1 expression at this level. Furthermore we have analysed the value of protein p27KIP1 expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between p27KIP1 expression and other clinic and pathologic parameters.

[Prognostic value of the immunohistochemical expresion of protein Rb in epidermoid carcinoma of the larynx]. / Valor pronóstico de la expresión inmunohistoquímica de la proteína Rb en el carcinoma epidermoide de laringe.

In this paper we carried out an immunohistochemical study of protein Rb (G3-245) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain) for a time of 5 years. In the cases with lymph node metastasis we also studied Rb expression at this level. Furthermore we have analysed the value of Rb expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between Rb expression and other clinic and pathologic parameters.

[Prognosis value of the immunohystochemical expresion of the p21WAF1 in the larynx cancer]. / Valor pronóstico de la expresión inmunohistoquímica de la proteina p21WAF1 en cáncer de laringe.

In this paper we carried out an immunohistochemical study of protein p21WAF1 (EA10) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain). In the cases with lymph node metastasis we also studied p21WAF1 expression at this level. Furthermore we have analysed the value of protein p21WAF1 expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we evaluate the relationship between p21WAF1 expression and other clinic and pathologic parameters.

[Prognosis value of the immunohistochemical expresion of the bcl-2 in the larynx epidermoid cancer]. / Valor pronóstico de la expresión inmunohistoquímica de la proteina bcl-2 en carcinoma de laringe.

In this paper we carried out an immunohistochemical study of bcl-2 protein expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at "Virgen de la Salud" Hospital (Toledo, Spain). In the cases with lymphonode metastasis we also analysed bcl-2 protein expression at this level. Furthermore we have studied the value of bcl-2 protein expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we analysed the relationship between bcl-2 protein expression and other clinic and pathologic parameters.

[Laryngeal actinomycosis]. / Actinomicosis laríngea.

Actinomycosis is a rare infectious disease in our practice and clinically it is charactherized by the presence of granulomatous lesions of subacute or chronic evolution. Most of the cases of actinomycosis are localised in the cervico-facial area, being the laryngeal one uncommon. We present a clinical case of a 53 years-old male diagnosed of primary laryngeal actinomycosis and we realise a bibliographic revision on this subject emphazising the diagnosis techniques and the differential diagnosis of this kind of lesions.

Actinomicosis laríngea / Laryngeal actinomycosìs

La actinomicosis es una enfermedad infecciosa poco común en nuestro medio que clínicamente se caracteriza por la presencia de lesiones granulomatosas de evolución subaguda o crónica. La mayoría de los casos de actinomicosis se producen en la región cervico-facial, siendo la localización laríngea rara. Presentamos el caso clínico de un varón de 53 años diagnosticado de actinomicosis laríngea primaria y realizamos una revisión bibliográfica del tema, haciendo especial hincapié en las técnicas diagnósticas y en el diagnóstico diferencial que este tipo de lesiones nos pueden plantear en la práctica clínica diaria (AU)

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[Inmunohistochimic expresion of p53 protein and TTS prognostic value in the larynx cancer]. / Expresión inmunohistoquímica de la proteina p53 y su valor pronóstico en el cancer de laringe.

We carried out an immunohistochemical study of p53 (DO7) expression in a series of 195 patients with laryngeal squamous cell carcinoma, treated and followed at the Department of Otolaryngology Virgen de la Salud Hospital (Toledo, Spain). In the cases with lymph node metastasis we also studied p53 expression at this site. We have investigated the value of p53 expression as a prognostic factor (tumor recurrence, deads due tu cancer and survival) and we have evaluated the relationship between p53 expression and other clinicopathologic characteristics.

[Pronostic value of the MDM-2 protein expression in the larynx cancer]. / Valor pronóstico de la expresión de la proteina MDM-2 en cancer de laringe.

In this paper we carried out an immunohistochemical study of Mdm-2 (IF2) expression in a series of 195 patients with laryngeal carcinoma that were diagnosticated, treated and followed at the Department of Otolaryngology at Virgen de la Salud Hospital (Toledo, Spain). In the cases with lymph node metastasis we also studied Mdm-2 expression at this level. We also wanted to investigate the value of Mdm-2 expression as a prognostic factor (tumor recurrence, deads due to cancer and survival) and we have evaluated the relationship between Mdm-2 expression and other clinic and pathologic characteristics.

[Metastasizing hypernephroma in palatine tonsil]. / Metástasis de hipernefroma en amígdala palatina.

Metastatic growths on palatine tonsils are very scarce if compared with primordial tumors of this sitting. Report of a case, in a 56-year-old woman, who 6 months after being operated from a left nephrectomy for hypernephroma presented a metastasis of clair renal cells on the right tonsil. Given the peculiarity of such a case we look through the literature of tonsil metastases and discuss the differential diagnosis regarding these type of lesions, sometimes encountered in our daily practice.

[Outpatient ENT hospital emergencies: a descriptive study of one year of services]. / Urgencias externas O.R.L. a nivel hospitalario: estudio descriptivo de un año de asistencia.

A descriptive and retrospective scrutiny dealing with 2,638 emergency cases admitted at "Virgen de la Salud" Hospital, Toledo, during 1993. Analysis of a series of parameters as age, sex, hour, day of the week, month, kind of pathology, emergency ward in charge of the exigency and so on, and correlation of these items. Assessment of the gravity of each urgent case and motive of admission. Our results are confronted with those given by other authors.

[Nodular paragranuloma (Hodgkin's disease) of the tonsil]. / Paragranuloma nodular (enfermedad de Hodgkin) de amígdala palatina.

Primitive involvement of the palatine tonsil with a nodular paragranuloma (nodular subtype of Hodgkin's malady with lymphocytic predominance) is rarely found, being larger in number the cases associated with simultaneous occurrence in other organs. In the paper the AA. report one of this instances sitting solitarily in the palatine amygdala (stadium IA). Furthermore a bibliographic review about Waldeyer's ring lymphoma and particularly on nodular Hodgkin's paragranuloma is displayed.